null

SMILES: Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1

InChI Key: InChIKey=BHPBVHSFDSZGKN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 319646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair