BDBM320390 2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyridine-7- carboxylic acid::US10174026, Example 34::US9738637, Example 34

SMILES: COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1

InChI Key: InChIKey=ZKGHEBCTAUNSED-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 320390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM320390 (2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyri...) Show SMILES COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-4-2-3-10(8-12)7-11-9-14-15(18-11)13(16(19)20)5-6-17-14/h2-6,8-9,18H,7H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				US Patent US10174026 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FG4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM320390 (2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyri...) Show SMILES COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-4-2-3-10(8-12)7-11-9-14-15(18-11)13(16(19)20)5-6-17-14/h2-6,8-9,18H,7H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				US Patent US10174026 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FG4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM320390 (2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyri...) Show SMILES COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-4-2-3-10(8-12)7-11-9-14-15(18-11)13(16(19)20)5-6-17-14/h2-6,8-9,18H,7H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quantical Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US9738637 (2017) BindingDB Entry DOI: 10.7270/Q2VD71K6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM320390 (2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyri...) Show SMILES COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-4-2-3-10(8-12)7-11-9-14-15(18-11)13(16(19)20)5-6-17-14/h2-6,8-9,18H,7H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quantical Research, Inc. US Patent					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				US Patent US9738637 (2017) BindingDB Entry DOI: 10.7270/Q2VD71K6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM320390 (2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyri...) Show SMILES COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-4-2-3-10(8-12)7-11-9-14-15(18-11)13(16(19)20)5-6-17-14/h2-6,8-9,18H,7H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quantical Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				US Patent US9738637 (2017) BindingDB Entry DOI: 10.7270/Q2VD71K6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM320390 (2-[(3-methoxyphenyl)methyl]- 1H-pyrrolo[3,2-b]pyri...) Show SMILES COc1cccc(Cc2cc3nccc(C(O)=O)c3[nH]2)c1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-4-2-3-10(8-12)7-11-9-14-15(18-11)13(16(19)20)5-6-17-14/h2-6,8-9,18H,7H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174026 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FG4
					More data for this Ligand-Target Pair