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SMILES: Cn1cc(cn1)-c1nc(N2CCOCC2)c2nc([nH]c2n1)C(=O)N1CCNCC1

InChI Key: InChIKey=UJJOUHQTDNGKJY-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320474   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))		BDBM320474
PNG
(US10174035, Compound 20 | [2-(1-Methyl-1H-pyrazol-...)
Show SMILES Cn1cc(cn1)-c1nc(N2CCOCC2)c2nc([nH]c2n1)C(=O)N1CCNCC1
Show InChI InChI=1S/C18H23N9O2/c1-25-11-12(10-20-25)14-22-15-13(17(24-14)26-6-8-29-9-7-26)21-16(23-15)18(28)27-4-2-19-3-5-27/h10-11,19H,2-9H2,1H3,(H,21,22,23,24)
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KEGG

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PC cid
PC sid
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US Patent
n/an/a 86n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...

US Patent US10174035 (2019)


BindingDB Entry DOI: 10.7270/Q2FB552Z
More data for this
Ligand-Target Pair