BindingDB PrimarySearch

BDBM3205 (+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydroxybenzyl)cyclopentyl]oxy]carbonyl]phenyl]carbonyl]-3-hydroxybenzoate::(1R,2S)-2-[(4-hydroxyphenyl)methyl]cyclopentyl 3,5-dihydroxy-4-{[2-hydroxy-6-(methoxycarbonyl)phenyl]carbonyl}benzoate::Balanol Analog 29c

SMILES: COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCC[C@H]1Cc1ccc(O)cc1

InChI Key: InChIKey=KSITVHDHIJKJBG-QMHKHESXSA-N

Data: 15 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 3205
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C beta II				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C eta				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C beta II				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C delta				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C gamma				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C epsilon				Bioorg Med Chem Lett 6: 1759-1764 (1996) Article DOI: 10.1016/0960-894X(96)00311-3 BindingDB Entry DOI: 10.7270/Q2QR4X3R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM3205 ((+/-)-anti-Methyl 2-[[2,6-dihydroxy-4-[[[2-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
Sphinx Laboratories					More data for this Ligand-Target Pair