null

SMILES: C[C@H]1CN(CCCNC(=O)c2nc3c(nc(nc3[nH]2)-c2cnn(C)c2)N2CCOCC2)C[C@@H](C)O1

InChI Key: InChIKey=RCSKGQVEJHQING-IYBDPMFKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 320530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320530 (N-{3-[cis-2,6-dimethylmorpholin-4-yl]propyl}-2-(1-...) Show SMILES C[C@H]1CN(CCCNC(=O)c2nc3c(nc(nc3[nH]2)-c2cnn(C)c2)N2CCOCC2)C[C@@H](C)O1 Show InChI InChI=1S/C23H33N9O3/c1-15-12-31(13-16(2)35-15)6-4-5-24-23(33)21-26-18-20(28-21)27-19(17-11-25-30(3)14-17)29-22(18)32-7-9-34-10-8-32/h11,14-16H,4-10,12-13H2,1-3H3,(H,24,33)(H,26,27,28,29)/t15-,16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM320530 (N-{3-[cis-2,6-dimethylmorpholin-4-yl]propyl}-2-(1-...) Show SMILES C[C@H]1CN(CCCNC(=O)c2nc3c(nc(nc3[nH]2)-c2cnn(C)c2)N2CCOCC2)C[C@@H](C)O1 Show InChI InChI=1S/C23H33N9O3/c1-15-12-31(13-16(2)35-15)6-4-5-24-23(33)21-26-18-20(28-21)27-19(17-11-25-30(3)14-17)29-22(18)32-7-9-34-10-8-32/h11,14-16H,4-10,12-13H2,1-3H3,(H,24,33)(H,26,27,28,29)/t15-,16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320530 (N-{3-[cis-2,6-dimethylmorpholin-4-yl]propyl}-2-(1-...) Show SMILES C[C@H]1CN(CCCNC(=O)c2nc3c(nc(nc3[nH]2)-c2cnn(C)c2)N2CCOCC2)C[C@@H](C)O1 Show InChI InChI=1S/C23H33N9O3/c1-15-12-31(13-16(2)35-15)6-4-5-24-23(33)21-26-18-20(28-21)27-19(17-11-25-30(3)14-17)29-22(18)32-7-9-34-10-8-32/h11,14-16H,4-10,12-13H2,1-3H3,(H,24,33)(H,26,27,28,29)/t15-,16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM320530 (N-{3-[cis-2,6-dimethylmorpholin-4-yl]propyl}-2-(1-...) Show SMILES C[C@H]1CN(CCCNC(=O)c2nc3c(nc(nc3[nH]2)-c2cnn(C)c2)N2CCOCC2)C[C@@H](C)O1 Show InChI InChI=1S/C23H33N9O3/c1-15-12-31(13-16(2)35-15)6-4-5-24-23(33)21-26-18-20(28-21)27-19(17-11-25-30(3)14-17)29-22(18)32-7-9-34-10-8-32/h11,14-16H,4-10,12-13H2,1-3H3,(H,24,33)(H,26,27,28,29)/t15-,16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human))	BDBM320530 (N-{3-[cis-2,6-dimethylmorpholin-4-yl]propyl}-2-(1-...) Show SMILES C[C@H]1CN(CCCNC(=O)c2nc3c(nc(nc3[nH]2)-c2cnn(C)c2)N2CCOCC2)C[C@@H](C)O1 Show InChI InChI=1S/C23H33N9O3/c1-15-12-31(13-16(2)35-15)6-4-5-24-23(33)21-26-18-20(28-21)27-19(17-11-25-30(3)14-17)29-22(18)32-7-9-34-10-8-32/h11,14-16H,4-10,12-13H2,1-3H3,(H,24,33)(H,26,27,28,29)/t15-,16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair