null

SMILES: CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1

InChI Key: InChIKey=YWPSNNQVCNRFAG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 321269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM321269 (N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chloro...) Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1 Show InChI InChI=1S/C19H23ClN2O/c1-22(15-12-16-6-3-2-4-7-16)14-5-13-21-19(23)17-8-10-18(20)11-9-17/h2-4,6-11H,5,12-15H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) US Patent					Assay Description The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...				US Patent US10179761 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MBG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM321269 (N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chloro...) Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1 Show InChI InChI=1S/C19H23ClN2O/c1-22(15-12-16-6-3-2-4-7-16)14-5-13-21-19(23)17-8-10-18(20)11-9-17/h2-4,6-11H,5,12-15H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universities of Lille Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from S1R in human Jurkat cell membranes after 2 hrs by liquid scintillation counting				Eur J Med Chem 138: 964-978 (2017) Article DOI: 10.1016/j.ejmech.2017.07.014 BindingDB Entry DOI: 10.7270/Q2GT5QQ7
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM321269 (N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chloro...) Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1 Show InChI InChI=1S/C19H23ClN2O/c1-22(15-12-16-6-3-2-4-7-16)14-5-13-21-19(23)17-8-10-18(20)11-9-17/h2-4,6-11H,5,12-15H2,1H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universities of Lille Curated by ChEMBL					Assay Description Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation counting				Eur J Med Chem 138: 964-978 (2017) Article DOI: 10.1016/j.ejmech.2017.07.014 BindingDB Entry DOI: 10.7270/Q2GT5QQ7
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM321269 (N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chloro...) Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1 Show InChI InChI=1S/C19H23ClN2O/c1-22(15-12-16-6-3-2-4-7-16)14-5-13-21-19(23)17-8-10-18(20)11-9-17/h2-4,6-11H,5,12-15H2,1H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) US Patent					Assay Description The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...				US Patent US10179761 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MBG
					More data for this Ligand-Target Pair