BDBM321381 N-[4-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]methanesulfonamide::US10183009, Example 34

SMILES: CC=CCn1cc(-c2ccc(NS(C)(=O)=O)cc2)c2cc[nH]c2c1=O

InChI Key: InChIKey=CEQYGBVWSKWBDP-ONEGZZNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BRD9 (aa 134-239) (Homo sapiens (Human))	BDBM321381 (N-[4-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-...) Show SMILES CC=CCn1cc(-c2ccc(NS(C)(=O)=O)cc2)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H19N3O3S/c1-3-4-11-21-12-16(15-9-10-19-17(15)18(21)22)13-5-7-14(8-6-13)20-25(2,23)24/h3-10,12,19-20H,11H2,1-2H3/b4-3+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair