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SMILES: CC=CCn1cc(-c2ccc(cc2)C(=O)N2CCOCC2)c2cc[nH]c2c1=O

InChI Key: InChIKey=JGOZUFGBTSAWEI-NSCUHMNNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321383   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 9 [134-239]


(Homo sapiens (Human))		BDBM321383
PNG
(6-but-2-enyl-4-[4-(morpholine-4-carbonyl)phenyl]-1...)
Show SMILES CC=CCn1cc(-c2ccc(cc2)C(=O)N2CCOCC2)c2cc[nH]c2c1=O
Show InChI InChI=1S/C22H23N3O3/c1-2-3-10-25-15-19(18-8-9-23-20(18)22(25)27)16-4-6-17(7-5-16)21(26)24-11-13-28-14-12-24/h2-9,15,23H,10-14H2,1H3/b3-2+
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...

US Patent US10183009 (2019)


BindingDB Entry DOI: 10.7270/Q2125VRQ
More data for this
Ligand-Target Pair