BDBM321398 3-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl]-4-methoxy-N-propyl-benzamide::US10183009, Example 74

SMILES: CCCNC(=O)c1ccc(OC)c(c1)-c1cn(C\C=C\C)c(=O)c2[nH]ccc12

InChI Key: InChIKey=FBZYIJXHMKVMDI-GQCTYLIASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BRD9 (aa 134-239) (Homo sapiens (Human))	BDBM321398 (3-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES CCCNC(=O)c1ccc(OC)c(c1)-c1cn(C\C=C\C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H25N3O3/c1-4-6-12-25-14-18(16-9-11-23-20(16)22(25)27)17-13-15(7-8-19(17)28-3)21(26)24-10-5-2/h4,6-9,11,13-14,23H,5,10,12H2,1-3H3,(H,24,26)/b6-4+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair