BDBM321436 4-[4-[3-(3-aminopyrazol-1-yl)azetidine-1-carbonyl]phenyl]-6-[(E)-but-2-enyl]-2-methyl-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 118

SMILES: C\C=C\Cn1cc(-c2ccc(cc2)C(=O)N2CC(C2)n2ccc(N)n2)c2cc(C)[nH]c2c1=O

InChI Key: InChIKey=IGQRSYBTCTXIRH-ONEGZZNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BRD9 (aa 134-239) (Homo sapiens (Human))	BDBM321436 (4-[4-[3-(3-aminopyrazol-1-yl)azetidine-1-carbonyl]...) Show SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(=O)N2CC(C2)n2ccc(N)n2)c2cc(C)[nH]c2c1=O Show InChI InChI=1S/C25H26N6O2/c1-3-4-10-29-15-21(20-12-16(2)27-23(20)25(29)33)17-5-7-18(8-6-17)24(32)30-13-19(14-30)31-11-9-22(26)28-31/h3-9,11-12,15,19,27H,10,13-14H2,1-2H3,(H2,26,28)/b4-3+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair