BDBM321453 3-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N-methyl-benzamide::US10183009, Example 25

SMILES: CNC(=O)c1cccc(c1)-c1cn(CC=CC)c(=O)c2[nH]ccc12

InChI Key: InChIKey=ZKGGJHHTHOEQMD-ONEGZZNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CECR2 (aa 424-538) (Homo sapiens (Human))	BDBM321453 (3-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES CNC(=O)c1cccc(c1)-c1cn(CC=CC)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C19H19N3O2/c1-3-4-10-22-12-16(15-8-9-21-17(15)19(22)24)13-6-5-7-14(11-13)18(23)20-2/h3-9,11-12,21H,10H2,1-2H3,(H,20,23)/b4-3+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair