BDBM3217 3-hydroxy-2-{[4-({[(1R,2R)-2-[(4-hydroxybenzene)amido]cyclopentyl]oxy}carbonyl)phenyl]carbonyl}benzoic acid::Modified Benzophenone Ring, Balanol Analog 17::trans-1-[4-(2-Carboxy-6-hydroxybenzoyl)benzoyloxy]-2-(4-hydroxybenzamido)cyclopentane

SMILES: OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1

InChI Key: InChIKey=IDYKIRFVJVFVPN-IFMALSPDSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM3217 (3-hydroxy-2-{[4-({[(1R,2R)-2-[(4-hydroxybenzene)am...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C27H23NO8/c29-18-13-11-16(12-14-18)25(32)28-20-4-2-6-22(20)36-27(35)17-9-7-15(8-10-17)24(31)23-19(26(33)34)3-1-5-21(23)30/h1,3,5,7-14,20,22,29-30H,2,4,6H2,(H,28,32)(H,33,34)/t20-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 45: 2624-43 (2002) Article DOI: 10.1021/jm020018f BindingDB Entry DOI: 10.7270/Q2BG2M50
					More data for this Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM3217 (3-hydroxy-2-{[4-({[(1R,2R)-2-[(4-hydroxybenzene)am...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C27H23NO8/c29-18-13-11-16(12-14-18)25(32)28-20-4-2-6-22(20)36-27(35)17-9-7-15(8-10-17)24(31)23-19(26(33)34)3-1-5-21(23)30/h1,3,5,7-14,20,22,29-30H,2,4,6H2,(H,28,32)(H,33,34)/t20-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 45: 2624-43 (2002) Article DOI: 10.1021/jm020018f BindingDB Entry DOI: 10.7270/Q2BG2M50
					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM3217 (3-hydroxy-2-{[4-({[(1R,2R)-2-[(4-hydroxybenzene)am...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C27H23NO8/c29-18-13-11-16(12-14-18)25(32)28-20-4-2-6-22(20)36-27(35)17-9-7-15(8-10-17)24(31)23-19(26(33)34)3-1-5-21(23)30/h1,3,5,7-14,20,22,29-30H,2,4,6H2,(H,28,32)(H,33,34)/t20-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 45: 2624-43 (2002) Article DOI: 10.1021/jm020018f BindingDB Entry DOI: 10.7270/Q2BG2M50
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM3217 (3-hydroxy-2-{[4-({[(1R,2R)-2-[(4-hydroxybenzene)am...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1)C(=O)O[C@@H]1CCC[C@H]1NC(=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C27H23NO8/c29-18-13-11-16(12-14-18)25(32)28-20-4-2-6-22(20)36-27(35)17-9-7-15(8-10-17)24(31)23-19(26(33)34)3-1-5-21(23)30/h1,3,5,7-14,20,22,29-30H,2,4,6H2,(H,28,32)(H,33,34)/t20-,22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 45: 2624-43 (2002) Article DOI: 10.1021/jm020018f BindingDB Entry DOI: 10.7270/Q2BG2M50
					More data for this Ligand-Target Pair