BDBM322553 US10183940, Example 6

SMILES: CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12

InChI Key: InChIKey=GAZPBBFJXPJWIL-UHFFFAOYSA-N

Data: 5 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 322553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM322553 (US10183940, Example 6) Show SMILES CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12 Show InChI InChI=1S/C22H23N3O2/c1-22(2,18-10-11-24-19-9-4-3-7-16(18)19)25-21(26)17-8-5-6-15-14-23-12-13-27-20(15)17/h3-11,23H,12-14H2,1-2H3,(H,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...				US Patent US10183940 (2019) BindingDB Entry DOI: 10.7270/Q2KW5J45
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM322553 (US10183940, Example 6) Show SMILES CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12 Show InChI InChI=1S/C22H23N3O2/c1-22(2,18-10-11-24-19-9-4-3-7-16(18)19)25-21(26)17-8-5-6-15-14-23-12-13-27-20(15)17/h3-11,23H,12-14H2,1-2H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...				US Patent US10183940 (2019) BindingDB Entry DOI: 10.7270/Q2KW5J45
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM322553 (US10183940, Example 6) Show SMILES CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12 Show InChI InChI=1S/C22H23N3O2/c1-22(2,18-10-11-24-19-9-4-3-7-16(18)19)25-21(26)17-8-5-6-15-14-23-12-13-27-20(15)17/h3-11,23H,12-14H2,1-2H3,(H,25,26)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...				US Patent US10183940 (2019) BindingDB Entry DOI: 10.7270/Q2KW5J45
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM322553 (US10183940, Example 6) Show SMILES CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12 Show InChI InChI=1S/C22H23N3O2/c1-22(2,18-10-11-24-19-9-4-3-7-16(18)19)25-21(26)17-8-5-6-15-14-23-12-13-27-20(15)17/h3-11,23H,12-14H2,1-2H3,(H,25,26)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...				US Patent US10183940 (2019) BindingDB Entry DOI: 10.7270/Q2KW5J45
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM322553 (US10183940, Example 6) Show SMILES CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12 Show InChI InChI=1S/C22H23N3O2/c1-22(2,18-10-11-24-19-9-4-3-7-16(18)19)25-21(26)17-8-5-6-15-14-23-12-13-27-20(15)17/h3-11,23H,12-14H2,1-2H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...				US Patent US10183940 (2019) BindingDB Entry DOI: 10.7270/Q2KW5J45
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM322553 (US10183940, Example 6) Show SMILES CC(C)(NC(=O)c1cccc2CNCCOc12)c1ccnc2ccccc12 Show InChI InChI=1S/C22H23N3O2/c1-22(2,18-10-11-24-19-9-4-3-7-16(18)19)25-21(26)17-8-5-6-15-14-23-12-13-27-20(15)17/h3-11,23H,12-14H2,1-2H3,(H,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.40	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10183940 (2019) BindingDB Entry DOI: 10.7270/Q2KW5J45
					More data for this Ligand-Target Pair