BDBM323490 (1,2-Trans)-2-((3-((R)-3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Cyclohexyl Acetate::US10188615, Example 173::US10639286, Example 173

SMILES: CC(=O)O[C@@H]1CCCC[C@H]1COc1cccc(c1)[C@H](O)CCN

InChI Key: InChIKey=QVFHDMUQYSVRAM-CGTJXYLNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinaldehyde-binding protein 1 (Homo sapiens (Human))	BDBM323490 ((1,2-Trans)-2-((3-((R)-3-Amino-1-Hydroxypropyl)Phe...) Show SMILES CC(=O)O[C@@H]1CCCC[C@H]1COc1cccc(c1)[C@H](O)CCN |r| Show InChI InChI=1S/C18H27NO4/c1-13(20)23-18-8-3-2-5-15(18)12-22-16-7-4-6-14(11-16)17(21)9-10-19/h4,6-7,11,15,17-18,21H,2-3,5,8-10,12,19H2,1H3/t15-,17+,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ACUCELA INC. US Patent					Assay Description Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).				US Patent US10639286 (2020)
					More data for this Ligand-Target Pair
Retinoid isomerohydrolase (Homo sapiens (Human))	BDBM323490 ((1,2-Trans)-2-((3-((R)-3-Amino-1-Hydroxypropyl)Phe...) Show SMILES CC(=O)O[C@@H]1CCCC[C@H]1COc1cccc(c1)[C@H](O)CCN |r| Show InChI InChI=1S/C18H27NO4/c1-13(20)23-18-8-3-2-5-15(18)12-22-16-7-4-6-14(11-16)17(21)9-10-19/h4,6-7,11,15,17-18,21H,2-3,5,8-10,12,19H2,1H3/t15-,17+,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ACUCELA INC. US Patent					Assay Description Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...				US Patent US10188615 (2019) BindingDB Entry DOI: 10.7270/Q2NP26HC
					More data for this Ligand-Target Pair