null
SMILES: ONC(=O)c1ccc(cc1)C1=Nc2ccccc2Oc2ccccc12
InChI Key: InChIKey=ZBYQBWHQMGPCBT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM323697 (US10188756, Compound CN54) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 56.1 | n/a | n/a | n/a | n/a | n/a | n/a |
The General Hospital Corporation US Patent | Assay Description All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a... | US Patent US10188756 (2019) BindingDB Entry DOI: 10.7270/Q20Z75CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM323697 (US10188756, Compound CN54) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
The General Hospital Corporation US Patent | Assay Description All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a... | US Patent US10188756 (2019) BindingDB Entry DOI: 10.7270/Q20Z75CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM323697 (US10188756, Compound CN54) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 53.7 | n/a | n/a | n/a | n/a | n/a | n/a |
The General Hospital Corporation US Patent | Assay Description All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a... | US Patent US10188756 (2019) BindingDB Entry DOI: 10.7270/Q20Z75CX | |||||||||||
More data for this Ligand-Target Pair |