BDBM323772 4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-[(methoxymethyl)sulfanyl]benzoic acid::US10189788, Example 52
SMILES: COCSc1cc(ccc1NC(=O)c1c(C)c(nc2ccc(Br)cc12)-c1ccccc1)C(O)=O
InChI Key: InChIKey=QADJPQCTRBIXAF-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM323772![]() (4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbon...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w... | US Patent US10189788 (2019) BindingDB Entry DOI: 10.7270/Q2RF5X3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM323772![]() (4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbon...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS... | US Patent US10189788 (2019) BindingDB Entry DOI: 10.7270/Q2RF5X3B | |||||||||||
More data for this Ligand-Target Pair |