BDBM324799 9-(4-(2H-1,2,3-triazol-2-::US10189841, Compound I-5::US10399980, Compound I-5

SMILES: CC(C)COc1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1

InChI Key: InChIKey=WGJNDQRHXALTHJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324799 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) Show SMILES CC(C)COc1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1 Show InChI InChI=1S/C23H22N8O2/c1-15(2)14-33-22-18(4-3-9-24-22)20-25-12-19-21(29-20)30(23(32)28-19)13-16-5-7-17(8-6-16)31-26-10-11-27-31/h3-12,15H,13-14H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324799 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) Show SMILES CC(C)COc1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1 Show InChI InChI=1S/C23H22N8O2/c1-15(2)14-33-22-18(4-3-9-24-22)20-25-12-19-21(29-20)30(23(32)28-19)13-16-5-7-17(8-6-16)31-26-10-11-27-31/h3-12,15H,13-14H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair