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SMILES: CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)N3CCN(C)CC3)c2n1

InChI Key: InChIKey=KPJCEJMLLJZXJY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324967 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)N3CCN(C)CC3)c2n1 Show InChI InChI=1S/C29H32N8O/c1-20(2)23-6-4-5-7-24(23)27-30-18-25-28(32-27)36(29(38)31-25)19-21-8-10-22(11-9-21)37-13-12-26(33-37)35-16-14-34(3)15-17-35/h4-13,18,20H,14-17,19H2,1-3H3,(H,31,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324967 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)N3CCN(C)CC3)c2n1 Show InChI InChI=1S/C29H32N8O/c1-20(2)23-6-4-5-7-24(23)27-30-18-25-28(32-27)36(29(38)31-25)19-21-8-10-22(11-9-21)37-13-12-26(33-37)35-16-14-34(3)15-17-35/h4-13,18,20H,14-17,19H2,1-3H3,(H,31,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair