null

SMILES: CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)N3CCOCC3)c2n1

InChI Key: InChIKey=RTLHFMMTPSJNRX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324968 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)N3CCOCC3)c2n1 Show InChI InChI=1S/C28H29N7O2/c1-19(2)22-5-3-4-6-23(22)26-29-17-24-27(31-26)34(28(36)30-24)18-20-7-9-21(10-8-20)35-12-11-25(32-35)33-13-15-37-16-14-33/h3-12,17,19H,13-16,18H2,1-2H3,(H,30,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324968 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)N3CCOCC3)c2n1 Show InChI InChI=1S/C28H29N7O2/c1-19(2)22-5-3-4-6-23(22)26-29-17-24-27(31-26)34(28(36)30-24)18-20-7-9-21(10-8-20)35-12-11-25(32-35)33-13-15-37-16-14-33/h3-12,17,19H,13-16,18H2,1-2H3,(H,30,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair