null
SMILES: CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccc3C)c2n1
InChI Key: InChIKey=YPGRUCUPXQGRLH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human)) | BDBM324978 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc. US Patent | Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning... | US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human)) | BDBM324978 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc. US Patent | Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning... | US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR | |||||||||||
More data for this Ligand-Target Pair |