null

SMILES: CC(C)c1c(F)cccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-c3noc(C)n3)c2n1

InChI Key: InChIKey=XQVCJIOSDCGADW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324982 (2-(3-fluoro-2- | US10189841, Compound I-188 | US10...) Show SMILES CC(C)c1c(F)cccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-c3noc(C)n3)c2n1 Show InChI InChI=1S/C24H21FN6O2/c1-13(2)20-17(5-4-6-18(20)25)22-26-11-19-23(29-22)31(24(32)28-19)12-15-7-9-16(10-8-15)21-27-14(3)33-30-21/h4-11,13H,12H2,1-3H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324982 (2-(3-fluoro-2- | US10189841, Compound I-188 | US10...) Show SMILES CC(C)c1c(F)cccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-c3noc(C)n3)c2n1 Show InChI InChI=1S/C24H21FN6O2/c1-13(2)20-17(5-4-6-18(20)25)22-26-11-19-23(29-22)31(24(32)28-19)12-15-7-9-16(10-8-15)21-27-14(3)33-30-21/h4-11,13H,12H2,1-3H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair