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SMILES: CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3nccn3C3CCNCC3)c2n1

InChI Key: InChIKey=LSCQGVXBMUGFDP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 325293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325293 (2-(2-isopropylphenyl)- | US10189841, Compound I-49...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3nccn3C3CCNCC3)c2n1 Show InChI InChI=1S/C30H33N7O/c1-20(2)24-6-4-5-7-25(24)27-33-18-26-29(34-27)37(30(38)35(26)3)19-21-8-10-22(11-9-21)28-32-16-17-36(28)23-12-14-31-15-13-23/h4-11,16-18,20,23,31H,12-15,19H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325293 (2-(2-isopropylphenyl)- | US10189841, Compound I-49...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3nccn3C3CCNCC3)c2n1 Show InChI InChI=1S/C30H33N7O/c1-20(2)24-6-4-5-7-25(24)27-33-18-26-29(34-27)37(30(38)35(26)3)19-21-8-10-22(11-9-21)28-32-16-17-36(28)23-12-14-31-15-13-23/h4-11,16-18,20,23,31H,12-15,19H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325293 (2-(2-isopropylphenyl)- | US10189841, Compound I-49...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3nccn3C3CCNCC3)c2n1 Show InChI InChI=1S/C30H33N7O/c1-20(2)24-6-4-5-7-25(24)27-33-18-26-29(34-27)37(30(38)35(26)3)19-21-8-10-22(11-9-21)28-32-16-17-36(28)23-12-14-31-15-13-23/h4-11,16-18,20,23,31H,12-15,19H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair