BindingDB logo
myBDB logout

null

SMILES: CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1

InChI Key: InChIKey=YMOTZDNJTZOVGM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 325483   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10189845 (2019)


BindingDB Entry DOI: 10.7270/Q2Z03B7Q
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10189845 (2019)


BindingDB Entry DOI: 10.7270/Q2Z03B7Q
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10189845 (2019)


BindingDB Entry DOI: 10.7270/Q2Z03B7Q
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10189845 (2019)


BindingDB Entry DOI: 10.7270/Q2Z03B7Q
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Array BioPharma Inc.; Celgene Corporation

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10730880 (2020)


BindingDB Entry DOI: 10.7270/Q2CC13R9
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



ARRAY BIOPHARMA INC.; CELGENE CORPORATION

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US11028093 (2021)


BindingDB Entry DOI: 10.7270/Q2T156RN
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Array BioPharma Inc.; Celgene Corporation

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10730880 (2020)


BindingDB Entry DOI: 10.7270/Q2CC13R9
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



Array BioPharma Inc.; Celgene Corporation

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10730880 (2020)


BindingDB Entry DOI: 10.7270/Q2CC13R9
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



ARRAY BIOPHARMA INC.; CELGENE CORPORATION

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US11028093 (2021)


BindingDB Entry DOI: 10.7270/Q2T156RN
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



ARRAY BIOPHARMA INC.; CELGENE CORPORATION

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US11028093 (2021)


BindingDB Entry DOI: 10.7270/Q2T156RN
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



ARRAY BIOPHARMA INC.; CELGENE CORPORATION

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US11028093 (2021)


BindingDB Entry DOI: 10.7270/Q2T156RN
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM325483
PNG
((3-((2-(4-(4-(1-(pentan-3-yl)- 1H-pyrazol-4- yl)py...)
Show SMILES CCC(CC)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(CCNC2CC(CO)C2)c1 |(-.01,7,;-1.09,5.91,;-2.58,6.31,;-2.98,7.8,;-1.89,8.89,;-3.67,5.22,;-3.19,3.76,;-4.44,2.85,;-5.69,3.76,;-5.21,5.22,;-4.44,1.31,;-3.11,.54,;-3.11,-1,;-4.44,-1.77,;-5.77,-1,;-7.24,-1.47,;-8.14,-.23,;-7.24,1.02,;-5.77,.54,;-1.77,-1.77,;-.31,-1.29,;.6,-2.54,;-.31,-3.78,;.09,-5.27,;1.58,-5.67,;1.98,-7.16,;3.46,-7.55,;4.23,-8.89,;5.57,-8.12,;7.06,-8.52,;8.14,-7.43,;4.8,-6.78,;-1.77,-3.31,)|
Show InChI InChI=1S/C24H32N8O/c1-3-21(4-2)31-14-19(12-28-31)24-23-5-6-26-32(23)15-22(29-24)18-11-27-30(13-18)8-7-25-20-9-17(10-20)16-33/h5-6,11-15,17,20-21,25,33H,3-4,7-10,16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Array BioPharma Inc.; Celgene Corporation

US Patent


Assay Description
Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...


US Patent US10730880 (2020)


BindingDB Entry DOI: 10.7270/Q2CC13R9
More data for this
Ligand-Target Pair