null

SMILES: CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1

InChI Key: InChIKey=HGUMRBROBXBLAK-DUSLRRAJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 325551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc.; Celgene Corporation US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10730880 (2020)
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
ARRAY BIOPHARMA INC.; CELGENE CORPORATION US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US11028093 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM325551 (US10189845, Example 213B | US10189845, Example 214...) Show SMILES CCC(C1CC1)n1cc(cn1)-c1nc(cn2nccc12)-c1cnn(C[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C21H25N7O2/c1-2-19(14-3-4-14)27-10-16(8-24-27)21-20-5-6-22-28(20)12-18(25-21)15-7-23-26(9-15)11-17(30)13-29/h5-10,12,14,17,19,29-30H,2-4,11,13H2,1H3/t17-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US10189845 (2019) BindingDB Entry DOI: 10.7270/Q2Z03B7Q
					More data for this Ligand-Target Pair