BDBM325585 6-Chloro-8-{5-[1-(tetrahydro-pyran-4-yl)-piperidin-4-yl]-[1,3,4]oxadiazol-2-yl}-chroman-5-ylamine ::US9636335, 25

SMILES: Nc1c(Cl)cc(-c2nnc(o2)C2CCN(CC2)C2CCOCC2)c2OCCCc12

InChI Key: InChIKey=AWPOUNIUIDQWEX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM325585 (6-Chloro-8-{5-[1-(tetrahydro-pyran-4-yl)-piperidin...) Show SMILES Nc1c(Cl)cc(-c2nnc(o2)C2CCN(CC2)C2CCOCC2)c2OCCCc12 Show InChI InChI=1S/C21H27ClN4O3/c22-17-12-16(19-15(18(17)23)2-1-9-28-19)21-25-24-20(29-21)13-3-7-26(8-4-13)14-5-10-27-11-6-14/h12-14H,1-11,23H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
SUVEN LIFE SCIENCES LIMITED US Patent					Assay Description A stable CHO cell line expressing recombinant human 5-HT4 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offers a non...				US Patent US9636335 (2017) BindingDB Entry DOI: 10.7270/Q2PG1TTQ
					More data for this Ligand-Target Pair