BDBM327427 N-(3-{(1R,5S,6r)-3-[3-(4,4-difluorocyclohexyl)propyl]-6-ethyl-3-azabicyclo[3.1.0]hexan-6-yl}-4-fluorophenyl)cyclopropanesulfonamide ::US9663463, 5-(b)
SMILES: CCC1([C@H]2CN(CCCC3CCC(F)(F)CC3)C[C@@H]12)c1cc(NS(=O)(=O)C2CC2)ccc1F
InChI Key: InChIKey=FXDXCHLUPTZIEQ-OFFJZUQKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM327427![]() (N-(3-{(1R,5S,6r)-3-[3-(4,4-difluorocyclohexyl)prop...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
SANWA KAGAKU KENKYUSHO CO., LTD.; UBE INDUSTRIES, LTD. US Patent | Assay Description The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO... | US Patent US9663463 (2017) BindingDB Entry DOI: 10.7270/Q27946RR | |||||||||||
More data for this Ligand-Target Pair |