BDBM327447 1-(4-amino-2-methoxyphenyl)-3-[1-(cyclohexylmethyl)-4-piperidyl]propan-1-one::US9663465, 4

SMILES: COc1cc(N)ccc1C(=O)CCC1CCN(CC2CCCCC2)CC1

InChI Key: InChIKey=UHGWCPXBDDWAKP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM327447 (1-(4-amino-2-methoxyphenyl)-3-[1-(cyclohexylmethyl...) Show SMILES COc1cc(N)ccc1C(=O)CCC1CCN(CC2CCCCC2)CC1 Show InChI InChI=1S/C22H34N2O2/c1-26-22-15-19(23)8-9-20(22)21(25)10-7-17-11-13-24(14-12-17)16-18-5-3-2-4-6-18/h8-9,15,17-18H,2-7,10-14,16,23H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITE DE CAEN US Patent					Assay Description Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...				US Patent US9663465 (2017) BindingDB Entry DOI: 10.7270/Q23J3G2W
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM327447 (1-(4-amino-2-methoxyphenyl)-3-[1-(cyclohexylmethyl...) Show SMILES COc1cc(N)ccc1C(=O)CCC1CCN(CC2CCCCC2)CC1 Show InChI InChI=1S/C22H34N2O2/c1-26-22-15-19(23)8-9-20(22)21(25)10-7-17-11-13-24(14-12-17)16-18-5-3-2-4-6-18/h8-9,15,17-18H,2-7,10-14,16,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITE DE CAEN US Patent					Assay Description Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...				US Patent US9663465 (2017) BindingDB Entry DOI: 10.7270/Q23J3G2W
					More data for this Ligand-Target Pair