BDBM3276 4-(Benzylamino)quinazoline deriv. 27::4-N-benzylquinazoline-4,5-diamine

SMILES: Nc1cccc2ncnc(NCc3ccccc3)c12

InChI Key: InChIKey=MBUYMCKMFDNNPH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3276 (4-(Benzylamino)quinazoline deriv. 27 | 4-N-benzylq...) Show SMILES Nc1cccc2ncnc(NCc3ccccc3)c12 Show InChI InChI=1S/C15H14N4/c16-12-7-4-8-13-14(12)15(19-10-18-13)17-9-11-5-2-1-3-6-11/h1-8,10H,9,16H2,(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 38: 3482-7 (1995) Article DOI: 10.1021/jm00018a008 BindingDB Entry DOI: 10.7270/Q2319T3K
					More data for this Ligand-Target Pair