null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1

InChI Key: InChIKey=ZCVDBEVZVHBBJC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327864 (US10377742, Compound 3 | US9663496, Compound 3 | p...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C29H31F2N5O2/c30-25-6-1-22(2-7-25)20-33-11-15-35(16-12-33)28(37)24-5-10-27(32-19-24)29(38)36-17-13-34(14-18-36)21-23-3-8-26(31)9-4-23/h1-10,19H,11-18,20-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327864 (US10377742, Compound 3 | US9663496, Compound 3 | p...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C29H31F2N5O2/c30-25-6-1-22(2-7-25)20-33-11-15-35(16-12-33)28(37)24-5-10-27(32-19-24)29(38)36-17-13-34(14-18-36)21-23-3-8-26(31)9-4-23/h1-10,19H,11-18,20-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair