null
SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)NC2CCN(CC2)S(=O)(=O)c2ccc(cc2)C#N)cc1
InChI Key: InChIKey=MJVVGQPISJDCKE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human)) | BDBM327867 (N-(4-((4- cyanophenyl)sulfonyl) piperidin-4-yl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
Rigel Pharmaceuticals, Inc. US Patent | Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti... | US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human)) | BDBM327867 (N-(4-((4- cyanophenyl)sulfonyl) piperidin-4-yl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
Rigel Pharmaceuticals, Inc. US Patent | Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti... | US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8 | |||||||||||
More data for this Ligand-Target Pair |