null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)Nc2ccn(Cc3ccc(cc3)C#N)n2)cc1

InChI Key: InChIKey=RJDFHCCYYFFSBE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327870 (N-(1-(4-cyanobenzyl)- 1H-pyrazol-3-yl)-5-(4- (4- f...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)Nc2ccn(Cc3ccc(cc3)C#N)n2)cc1 Show InChI InChI=1S/C29H26FN7O2/c30-25-8-5-22(6-9-25)19-35-13-15-36(16-14-35)29(39)24-7-10-26(32-18-24)28(38)33-27-11-12-37(34-27)20-23-3-1-21(17-31)2-4-23/h1-12,18H,13-16,19-20H2,(H,33,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327870 (N-(1-(4-cyanobenzyl)- 1H-pyrazol-3-yl)-5-(4- (4- f...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)Nc2ccn(Cc3ccc(cc3)C#N)n2)cc1 Show InChI InChI=1S/C29H26FN7O2/c30-25-8-5-22(6-9-25)19-35-13-15-36(16-14-35)29(39)24-7-10-26(32-18-24)28(38)33-27-11-12-37(34-27)20-23-3-1-21(17-31)2-4-23/h1-12,18H,13-16,19-20H2,(H,33,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair