null

SMILES: COc1ccc(cc1)-c1ccc(NC(=O)c2ccc(cn2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1

InChI Key: InChIKey=DVMILXSBZSNOPF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327890 (N-(4-(4- methoxyphenyl)phenyl)- 5-(4-(4- fluoroben...) Show SMILES COc1ccc(cc1)-c1ccc(NC(=O)c2ccc(cn2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C31H29FN4O3/c1-39-28-13-6-24(7-14-28)23-4-11-27(12-5-23)34-30(37)29-15-8-25(20-33-29)31(38)36-18-16-35(17-19-36)21-22-2-9-26(32)10-3-22/h2-15,20H,16-19,21H2,1H3,(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327890 (N-(4-(4- methoxyphenyl)phenyl)- 5-(4-(4- fluoroben...) Show SMILES COc1ccc(cc1)-c1ccc(NC(=O)c2ccc(cn2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C31H29FN4O3/c1-39-28-13-6-24(7-14-28)23-4-11-27(12-5-23)34-30(37)29-15-8-25(20-33-29)31(38)36-18-16-35(17-19-36)21-22-2-9-26(32)10-3-22/h2-15,20H,16-19,21H2,1H3,(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair