null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(Nc3ccc(Cc4ccccc4)cc3)nc2)cc1

InChI Key: InChIKey=PXCXFGLKFBBGMD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327891 ((6-(4- benzylphenylamino) pyridin-3-yl)(4-(4- flu...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(Nc3ccc(Cc4ccccc4)cc3)nc2)cc1 Show InChI InChI=1S/C30H29FN4O/c31-27-11-6-25(7-12-27)22-34-16-18-35(19-17-34)30(36)26-10-15-29(32-21-26)33-28-13-8-24(9-14-28)20-23-4-2-1-3-5-23/h1-15,21H,16-20,22H2,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327891 ((6-(4- benzylphenylamino) pyridin-3-yl)(4-(4- flu...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(Nc3ccc(Cc4ccccc4)cc3)nc2)cc1 Show InChI InChI=1S/C30H29FN4O/c31-27-11-6-25(7-12-27)22-34-16-18-35(19-17-34)30(36)26-10-15-29(32-21-26)33-28-13-8-24(9-14-28)20-23-4-2-1-3-5-23/h1-15,21H,16-20,22H2,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair