null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)-c2ccc(cc2)C(=O)NCc2ccc(cc2)C#N)cc1

InChI Key: InChIKey=PTFCCBDWBUWRTB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327896 ((6-(4-(4- cyanobenzylcarbamoyl) phenyl)pyridin-3-...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)-c2ccc(cc2)C(=O)NCc2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C32H28FN5O2/c33-29-12-5-25(6-13-29)22-37-15-17-38(18-16-37)32(40)28-11-14-30(35-21-28)26-7-9-27(10-8-26)31(39)36-20-24-3-1-23(19-34)2-4-24/h1-14,21H,15-18,20,22H2,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327896 ((6-(4-(4- cyanobenzylcarbamoyl) phenyl)pyridin-3-...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)-c2ccc(cc2)C(=O)NCc2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C32H28FN5O2/c33-29-12-5-25(6-13-29)22-37-15-17-38(18-16-37)32(40)28-11-14-30(35-21-28)26-7-9-27(10-8-26)31(39)36-20-24-3-1-23(19-34)2-4-24/h1-14,21H,15-18,20,22H2,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair