null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(NC3CCN(Cc4ccc(cc4)C#N)CC3)nc2)cc1

InChI Key: InChIKey=AUSCOAAXXZHOLH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327897 ((6-(4- (cyanobenzyl)piperidin- 4-ylamino)pyridin-3...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(NC3CCN(Cc4ccc(cc4)C#N)CC3)nc2)cc1 Show InChI InChI=1S/C30H33FN6O/c31-27-8-5-25(6-9-27)22-36-15-17-37(18-16-36)30(38)26-7-10-29(33-20-26)34-28-11-13-35(14-12-28)21-24-3-1-23(19-32)2-4-24/h1-10,20,28H,11-18,21-22H2,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327897 ((6-(4- (cyanobenzyl)piperidin- 4-ylamino)pyridin-3...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(NC3CCN(Cc4ccc(cc4)C#N)CC3)nc2)cc1 Show InChI InChI=1S/C30H33FN6O/c31-27-8-5-25(6-9-27)22-36-15-17-37(18-16-36)30(38)26-7-10-29(33-20-26)34-28-11-13-35(14-12-28)21-24-3-1-23(19-32)2-4-24/h1-10,20,28H,11-18,21-22H2,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair