null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(Nc3ccc(cc3)-c3ccccc3)nc2)cc1

InChI Key: InChIKey=IDNTUUFQESKWJF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327898 ((6-(4- phenylphenylamino) pyridin-3-yl)(4-(4- flu...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(Nc3ccc(cc3)-c3ccccc3)nc2)cc1 Show InChI InChI=1S/C29H27FN4O/c30-26-11-6-22(7-12-26)21-33-16-18-34(19-17-33)29(35)25-10-15-28(31-20-25)32-27-13-8-24(9-14-27)23-4-2-1-3-5-23/h1-15,20H,16-19,21H2,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM327898 ((6-(4- phenylphenylamino) pyridin-3-yl)(4-(4- flu...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(Nc3ccc(cc3)-c3ccccc3)nc2)cc1 Show InChI InChI=1S/C29H27FN4O/c30-26-11-6-22(7-12-26)21-33-16-18-34(19-17-33)29(35)25-10-15-28(31-20-25)32-27-13-8-24(9-14-27)23-4-2-1-3-5-23/h1-15,20H,16-19,21H2,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair