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SMILES: CS(=O)(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(nn2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1

InChI Key: InChIKey=FFDTXEQOSUMYOS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328261   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5'-AMP-activated protein kinase catalytic subunit alpha-2


(Homo sapiens (Human))		BDBM328261
PNG
(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- (me...)
Show SMILES CS(=O)(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(nn2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1
Show InChI InChI=1S/C31H34N6O5S/c1-43(40,41)27-8-6-25(7-9-27)42-26-14-18-37(19-15-26)31(39)29-11-10-28(34-35-29)30(38)33-24-12-16-36(17-13-24)21-23-4-2-22(20-32)3-5-23/h2-11,24,26H,12-19,21H2,1H3,(H,33,38)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<500n/an/an/an/a



Rigel Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...

US Patent US9663496 (2017)


BindingDB Entry DOI: 10.7270/Q26975P8
More data for this
Ligand-Target Pair