null

SMILES: COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(nc1)C(=O)NC1CCN(Cc2ccc(NC(=O)CCOCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)cc2)CC1

InChI Key: InChIKey=HVUHUGNDUZGZJI-NVVQJRFUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328265 (5-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N...) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(nc1)C(=O)NC1CCN(Cc2ccc(NC(=O)CCOCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)cc2)CC1 |r| Show InChI InChI=1S/C51H68N8O10S/c1-66-41-13-8-36(9-14-41)48(62)37-16-24-59(25-17-37)50(64)38-10-15-42(53-32-38)49(63)55-40-18-22-58(23-19-40)33-35-6-11-39(12-7-35)54-46(61)20-26-67-28-30-69-31-29-68-27-21-52-45(60)5-3-2-4-44-47-43(34-70-44)56-51(65)57-47/h6-15,32,37,40,43-44,47H,2-5,16-31,33-34H2,1H3,(H,52,60)(H,54,61)(H,55,63)(H2,56,57,65)/t43-,44-,47-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328265 (5-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N...) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(nc1)C(=O)NC1CCN(Cc2ccc(NC(=O)CCOCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)cc2)CC1 |r| Show InChI InChI=1S/C51H68N8O10S/c1-66-41-13-8-36(9-14-41)48(62)37-16-24-59(25-17-37)50(64)38-10-15-42(53-32-38)49(63)55-40-18-22-58(23-19-40)33-35-6-11-39(12-7-35)54-46(61)20-26-67-28-30-69-31-29-68-27-21-52-45(60)5-3-2-4-44-47-43(34-70-44)56-51(65)57-47/h6-15,32,37,40,43-44,47H,2-5,16-31,33-34H2,1H3,(H,52,60)(H,54,61)(H,55,63)(H2,56,57,65)/t43-,44-,47-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair