null

SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CCN(CC2)c2ccc(cc2)C#N)cc1

InChI Key: InChIKey=MHLHQNWCMLCICH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328279 (N-(1-(4- cyanophenyl)piperidin- 4-yl)-6-(4-(4- flu...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CCN(CC2)c2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C30H31FN6O2/c31-25-6-1-23(2-7-25)21-35-15-17-37(18-16-35)30(39)28-10-5-24(20-33-28)29(38)34-26-11-13-36(14-12-26)27-8-3-22(19-32)4-9-27/h1-10,20,26H,11-18,21H2,(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328279 (N-(1-(4- cyanophenyl)piperidin- 4-yl)-6-(4-(4- flu...) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CCN(CC2)c2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C30H31FN6O2/c31-25-6-1-23(2-7-25)21-35-15-17-37(18-16-35)30(39)28-10-5-24(20-33-28)29(38)34-26-11-13-36(14-12-26)27-8-3-22(19-32)4-9-27/h1-10,20,26H,11-18,21H2,(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair