null

SMILES: O=C(NC1CCN(CC1)c1ccc(cc1)C#N)c1ccc(nc1)C(=O)N1CCC(CC1)Oc1ccc(cc1)C#N

InChI Key: InChIKey=AMGOYODSYQCBIL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328280 (6-(4-(4-cyanophenoxy) piperidine-1-carbonyl)- N-(...) Show SMILES O=C(NC1CCN(CC1)c1ccc(cc1)C#N)c1ccc(nc1)C(=O)N1CCC(CC1)Oc1ccc(cc1)C#N Show InChI InChI=1S/C31H30N6O3/c32-19-22-1-6-26(7-2-22)36-15-11-25(12-16-36)35-30(38)24-5-10-29(34-21-24)31(39)37-17-13-28(14-18-37)40-27-8-3-23(20-33)4-9-27/h1-10,21,25,28H,11-18H2,(H,35,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328280 (6-(4-(4-cyanophenoxy) piperidine-1-carbonyl)- N-(...) Show SMILES O=C(NC1CCN(CC1)c1ccc(cc1)C#N)c1ccc(nc1)C(=O)N1CCC(CC1)Oc1ccc(cc1)C#N Show InChI InChI=1S/C31H30N6O3/c32-19-22-1-6-26(7-2-22)36-15-11-25(12-16-36)35-30(38)24-5-10-29(34-21-24)31(39)37-17-13-28(14-18-37)40-27-8-3-23(20-33)4-9-27/h1-10,21,25,28H,11-18H2,(H,35,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair