null

SMILES: COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CCN(Cc2cccc(OC)c2)CC1

InChI Key: InChIKey=FIFRYWRXSPZTJD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328287 (6-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N...) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CCN(Cc2cccc(OC)c2)CC1 Show InChI InChI=1S/C33H38N4O5/c1-41-28-9-6-24(7-10-28)31(38)25-12-18-37(19-13-25)33(40)30-11-8-26(21-34-30)32(39)35-27-14-16-36(17-15-27)22-23-4-3-5-29(20-23)42-2/h3-11,20-21,25,27H,12-19,22H2,1-2H3,(H,35,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328287 (6-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)- N...) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cn1)C(=O)NC1CCN(Cc2cccc(OC)c2)CC1 Show InChI InChI=1S/C33H38N4O5/c1-41-28-9-6-24(7-10-28)31(38)25-12-18-37(19-13-25)33(40)30-11-8-26(21-34-30)32(39)35-27-14-16-36(17-15-27)22-23-4-3-5-29(20-23)42-2/h3-11,20-21,25,27H,12-19,22H2,1-2H3,(H,35,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair