null

SMILES: Fc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)Oc2cccc(NC(=O)C3CC3)c2)cc1

InChI Key: InChIKey=QSFYVVXENQIVBX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328294 (6-(4-(3-(cyclopropane- carboxamido)phenoxy) piper...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)Oc2cccc(NC(=O)C3CC3)c2)cc1 Show InChI InChI=1S/C34H38FN5O4/c35-26-9-4-23(5-10-26)22-39-16-12-27(13-17-39)37-33(42)25-8-11-31(36-21-25)34(43)40-18-14-29(15-19-40)44-30-3-1-2-28(20-30)38-32(41)24-6-7-24/h1-5,8-11,20-21,24,27,29H,6-7,12-19,22H2,(H,37,42)(H,38,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328294 (6-(4-(3-(cyclopropane- carboxamido)phenoxy) piper...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)Oc2cccc(NC(=O)C3CC3)c2)cc1 Show InChI InChI=1S/C34H38FN5O4/c35-26-9-4-23(5-10-26)22-39-16-12-27(13-17-39)37-33(42)25-8-11-31(36-21-25)34(43)40-18-14-29(15-19-40)44-30-3-1-2-28(20-30)38-32(41)24-6-7-24/h1-5,8-11,20-21,24,27,29H,6-7,12-19,22H2,(H,37,42)(H,38,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair