null

SMILES: CC(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(nn2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1

InChI Key: InChIKey=ACJLYGUYLHGBRM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328299 (6-(4-(4-acetylphenoxy) piperidine-1-carbonyl)- N-...) Show SMILES CC(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(nn2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1 Show InChI InChI=1S/C32H34N6O4/c1-22(39)25-6-8-27(9-7-25)42-28-14-18-38(19-15-28)32(41)30-11-10-29(35-36-30)31(40)34-26-12-16-37(17-13-26)21-24-4-2-23(20-33)3-5-24/h2-11,26,28H,12-19,21H2,1H3,(H,34,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US10377742 (2019) BindingDB Entry DOI: 10.7270/Q2RV0R22
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Homo sapiens (Human))	BDBM328299 (6-(4-(4-acetylphenoxy) piperidine-1-carbonyl)- N-...) Show SMILES CC(=O)c1ccc(OC2CCN(CC2)C(=O)c2ccc(nn2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1 Show InChI InChI=1S/C32H34N6O4/c1-22(39)25-6-8-27(9-7-25)42-28-14-18-38(19-15-28)32(41)30-11-10-29(35-36-30)31(40)34-26-12-16-37(17-13-26)21-24-4-2-23(20-33)3-5-24/h2-11,26,28H,12-19,21H2,1H3,(H,34,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<500	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...				US Patent US9663496 (2017) BindingDB Entry DOI: 10.7270/Q26975P8
					More data for this Ligand-Target Pair