BDBM328381 6-bromo-1-((4-methoxy-3-(4-methylpiperazin-1-yl)phenyl) sulfonyl)-1H-indole::US9663498, Example 21

SMILES: COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1ccc2ccc(Br)cc12

InChI Key: InChIKey=IKCJCGLRLPDWNC-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM328381 (6-bromo-1-((4-methoxy-3-(4-methylpiperazin-1-yl)ph...) Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1ccc2ccc(Br)cc12 Show InChI InChI=1S/C20H22BrN3O3S/c1-22-9-11-23(12-10-22)19-14-17(5-6-20(19)27-2)28(25,26)24-8-7-15-3-4-16(21)13-18(15)24/h3-8,13-14H,9-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...				US Patent US9663498 (2017) BindingDB Entry DOI: 10.7270/Q22N54C8
					More data for this Ligand-Target Pair