null
SMILES: COc1ccc(cc1N1CCN(CC1)C1CC1)S(=O)(=O)n1cc(C(F)F)c2ccc(Cl)cc12
InChI Key: InChIKey=LYMZAKGJYMLURF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM328396 (6-chloro-1-((3-(4-cyclopropylpiperazin-1-yl)-4-met...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0920 | n/a | n/a | n/a | n/a | n/a | n/a |
SUNSHINE LAKE PHARMA CO., LTD. US Patent | Assay Description The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo... | US Patent US9663498 (2017) BindingDB Entry DOI: 10.7270/Q22N54C8 | |||||||||||
More data for this Ligand-Target Pair |