BDBM330213 N-[4-[(1R,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]-2-(trifluoromethyl)pyridin-4-amine::US9663530, Example 57

SMILES: FC(F)(F)c1cc(ccn1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2

InChI Key: InChIKey=MUUHHVUOUYSABV-RHSMWYFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM330213 (N-[4-[(1R,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl...) Show SMILES FC(F)(F)c1cc(ccn1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2 |r| Show InChI InChI=1S/C18H16F3N3O2/c19-18(20,21)15-7-11(5-6-22-15)16(25)24-13-3-1-12(2-4-13)17-8-14(9-26-17)23-10-17/h1-7,14,23H,8-10H2,(H,24,25)/t14-,17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM330213 (N-[4-[(1R,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl...) Show SMILES FC(F)(F)c1cc(ccn1)C(=O)Nc1ccc(cc1)[C@@]12CN[C@@H](CO1)C2 |r| Show InChI InChI=1S/C18H16F3N3O2/c19-18(20,21)15-7-11(5-6-22-15)16(25)24-13-3-1-12(2-4-13)17-8-14(9-26-17)23-10-17/h1-7,14,23H,8-10H2,(H,24,25)/t14-,17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59.3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...				US Patent US9663530 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JMC
					More data for this Ligand-Target Pair