BDBM330348 US9725430, Compound 1e::US9962362, Compound 1e

SMILES: CC(O)Cc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1

InChI Key: InChIKey=SUAFCPJOVOKXGL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eyes absent homolog 3 (EYA3) (Homo sapiens (Human))	BDBM330348 (US9725430, Compound 1e | US9962362, Compound 1e) Show SMILES CC(O)Cc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 Show InChI InChI=1S/C18H14I2O4/c1-9(21)6-15-16(11-4-2-3-5-14(11)24-15)17(22)10-7-12(19)18(23)13(20)8-10/h2-5,7-9,21,23H,6H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
GNF					Assay Description The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...				Bioorg Med Chem Lett 16: 5488-92 (2006) BindingDB Entry DOI: 10.7270/Q2ZK5JZ7
					More data for this Ligand-Target Pair
Eyes absent homolog 3 (EYA3) (Homo sapiens (Human))	BDBM330348 (US9725430, Compound 1e | US9962362, Compound 1e) Show SMILES CC(O)Cc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 Show InChI InChI=1S/C18H14I2O4/c1-9(21)6-15-16(11-4-2-3-5-14(11)24-15)17(22)10-7-12(19)18(23)13(20)8-10/h2-5,7-9,21,23H,6H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
CHILDREN HOSPITAL MEDICAL CENTER US Patent					Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....				US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ
					More data for this Ligand-Target Pair