BDBM33206 thiazoloazepinyl acetamide, 5

SMILES: CC(=O)Nc1nc2CCCNC(=O)c2s1

InChI Key: InChIKey=OYHOEDBNAJPFKK-UHFFFAOYSA-N

Data: 2 Other

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM33206 (thiazoloazepinyl acetamide, 5) Show SMILES CC(=O)Nc1nc2CCCNC(=O)c2s1 Show InChI InChI=1S/C9H11N3O2S/c1-5(13)11-9-12-6-3-2-4-10-8(14)7(6)15-9/h2-4H2,1H3,(H,10,14)(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	23
The Institute of Cancer Research					Assay Description CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...				J Med Chem 52: 4810-9 (2009) Article DOI: 10.1021/jm900314j BindingDB Entry DOI: 10.7270/Q27W69KC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM33206 (thiazoloazepinyl acetamide, 5) Show SMILES CC(=O)Nc1nc2CCCNC(=O)c2s1 Show InChI InChI=1S/C9H11N3O2S/c1-5(13)11-9-12-6-3-2-4-10-8(14)7(6)15-9/h2-4H2,1H3,(H,10,14)(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	23
The Institute of Cancer Research					Assay Description AlphaScreen (PerkinElmer Life Sciences, Inc) was performed in opaque 384-well polypropylene plates. The assay relies on hydrogel coated Donor and Acc...				J Med Chem 52: 4810-9 (2009) Article DOI: 10.1021/jm900314j BindingDB Entry DOI: 10.7270/Q27W69KC
					More data for this Ligand-Target Pair				3D Structure (crystal)