null

SMILES: CCCc1cc2c(c(ccc2n1CC(C)(C)O)C#N)C(F)(F)F

InChI Key: InChIKey=UBRFDZVHGGUVEL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM332401 (US10196353, Example 12 | US11299457, Example 12) Show SMILES CCCc1cc2c(c(ccc2n1CC(C)(C)O)C#N)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-4-5-12-8-13-14(22(12)10-16(2,3)23)7-6-11(9-21)15(13)17(18,19)20/h6-8,23H,4-5,10H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332401 (US10196353, Example 12 | US11299457, Example 12) Show SMILES CCCc1cc2c(c(ccc2n1CC(C)(C)O)C#N)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-4-5-12-8-13-14(22(12)10-16(2,3)23)7-6-11(9-21)15(13)17(18,19)20/h6-8,23H,4-5,10H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair