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SMILES: C[C@@H](n1ccc2c(c(ccc12)C#N)C(F)(F)F)C(C)(C)O

InChI Key: InChIKey=RRWMFEXUNNLRMV-SECBINFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM332404 (US10196353, Example 22 | US11299457, Example 22) Show SMILES C[C@@H](n1ccc2c(c(ccc12)C#N)C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C15H15F3N2O/c1-9(14(2,3)21)20-7-6-11-12(20)5-4-10(8-19)13(11)15(16,17)18/h4-7,9,21H,1-3H3/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332404 (US10196353, Example 22 | US11299457, Example 22) Show SMILES C[C@@H](n1ccc2c(c(ccc12)C#N)C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C15H15F3N2O/c1-9(14(2,3)21)20-7-6-11-12(20)5-4-10(8-19)13(11)15(16,17)18/h4-7,9,21H,1-3H3/t9-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair